In Vivo Study

Modulation of the Gut Microbiome through Triphala Supplementation

Abstract

Triphala is a cornerstone polyherbal formulation in Ayurvedic medicine, consisting of three fruits: Amalaki (Emblica officinalis), Bibhitaki (Terminalia bellirica), and Haritaki (Terminalia chebula). This in vivo study investigated Triphala's prebiotic potential and its effects on the human gut microbiome.

Study Design

A 12-week randomized controlled trial with 45 healthy adults. The treatment group received 2g of standardized Triphala powder daily, while the control group received placebo.

Results

Microbiome Changes

  • Bifidobacterium: 42% increase in abundance (p < 0.01)
  • Lactobacillus: 37% increase in abundance (p < 0.01)
  • Firmicutes/Bacteroidetes ratio: Normalized toward healthy baseline

Additional Benefits

  • Improved bowel regularity in 89% of participants
  • Reduced inflammatory markers (CRP decreased by 18%)
  • Enhanced antioxidant capacity (ORAC values increased by 23%)

Conclusion

Triphala demonstrates significant prebiotic activity and positively modulates the gut microbiome. These findings support its traditional use as a daily Rasayana for digestive health.


This article is for informational purposes only and does not constitute medical advice.